Extracellular CIRP induces abnormal activation of fibroblast-like synoviocytes from patients with RA via the TLR4-mediated HDAC3 pathways
Yao Feng, Yingjie Zhao, Qiuxia Yu, Weirong Hu, Weirong Hu, Yi Lin, Yong Chen, Lin Li, Cheng Sun, Shufang Li, Ke Wang, Min Yang, Renpeng Zhou, Wei Hu, Wei Hu
Topics & Concepts
Proinflammatory cytokineExtracellularTLR4HDAC3Gene knockdownFibroblastCell biologyChemistryExtracellular matrixInflammationSignal transductionMedicineHistone deacetylaseBiologyImmunologyHistoneBiochemistryIn vitroApoptosisGeneInflammasome and immune disordersCancer-related molecular mechanisms researchImmune Response and Inflammation