Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs
Tian Li, Kun Wu, Zhenlei Yue, Yifei Wang, Fan Zhang, Huaizong Shen
Topics & Concepts
BiologyDrug discoveryPhosphatidylinositol 4,5-bisphosphateFenestrationPotassium channelElectrophysiologyNeuroscienceBiophysicsPhosphatidylinositolCell biologyBioinformaticsSignal transductionMedicineSurgeryIon channel regulation and functionCardiac electrophysiology and arrhythmiasForce Microscopy Techniques and Applications