Recommended tool compounds and drugs for blocking P2X and P2Y receptors
Christa E. Müller, Vigneshwaran Namasivayam
Abstract
This review article presents a collection of tool compounds that selectively block and are recommended for studying P2Y and P2X receptor subtypes, investigating their roles in physiology and validating them as future drug targets. Moreover, drug candidates and approved drugs for P2 receptors will be discussed.
Topics & Concepts
Blocking (statistics)Human physiologyReceptorDrugPharmacologyMedicineDrug discoveryBioinformaticsComputer scienceBiologyInternal medicineComputer networkAdenosine and Purinergic SignalingPharmacological Receptor Mechanisms and EffectsReceptor Mechanisms and Signaling