Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata
Rupali Gund, Angela M. Christiano
Abstract
: AA: alopecia areata; CQ: chloroquine; GWAS: genome-wide association studies; HF: hair follicle; MHC: major histocompatibility complex; SDLN: skin-draining lymph nodes.
Topics & Concepts
Alopecia areataAutophagyPathogenesisBiologyHair lossATG12Hair follicleImmune systemAutoimmune diseaseImmunologyAutoimmunityATG5Cancer researchEndocrinologyApoptosisGeneticsAntibodyAutophagy in Disease and TherapyHair Growth and DisordersCancer-related molecular mechanisms research