De novo design of DNA aptamers that target okadaic acid (OA) by docking-then-assembling of single nucleotides
Menghua Song, Yuanyuan Li, Ruihua Gao, Jianping Liu, Qiang Huang
Topics & Concepts
AptamerMicroscale thermophoresisSystematic evolution of ligands by exponential enrichmentSmall moleculeDocking (animal)Okadaic acidChemistryBiosensorCombinatorial chemistryNucleic acidNucleotideComputational biologyDNABiochemistryBiologyRNAMolecular biologyEnzymePhosphataseGeneNursingMedicineAdvanced biosensing and bioanalysis techniquesMass Spectrometry Techniques and ApplicationsBacterial Genetics and Biotechnology