The proteostasis guardian HSF1 directs the transcription of its paralog and interactor HSF2 during proteasome dysfunction
Silvia Santopolo, Anna Riccio, Antonio Rossi, M. Gabriella Santoro
Topics & Concepts
HSF1ProteostasisBiologyTranscription factorHeat shock factorProteasomeProteasome inhibitorChromatin immunoprecipitationCell biologyHeat shockBortezomibHeat shock proteinPromoterGene expressionGeneticsHsp70ImmunologyGeneMultiple myelomaHeat shock proteins researchEndoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathways