Luteolin attenuates cancer cell stemness in PTX-resistant oesophageal cancer cells through mediating SOX2 protein stability
Jinzhu Zhao, Leilei Li, Zhijia Wang, Linlin Li, Mingjing He, Shuhua Han, Yalong Dong, Xiaojie Liu, Wen Zhao, Yu Ke, Cong Wang
Topics & Concepts
Cancer researchCancer stem cellCancer cellEpithelial–mesenchymal transitionSOX2CancerProtein kinase BLuteolinPI3K/AKT/mTOR pathwaySKBR3PaclitaxelChemistryMetastasisStem cellBiologyPhosphorylationSignal transductionCell biologyBiochemistryFlavonoidTranscription factorHuman breastGeneticsAntioxidantGeneCancer Cells and MetastasisFerroptosis and cancer prognosisUbiquitin and proteasome pathways