Lactucaxanthin protects retinal pigment epithelium from hyperglycemia-regulated hypoxia/ER stress/VEGF pathway mediated angiogenesis in ARPE-19 cell and rat model
R Anitha, Rajasekar Janani, Peethambaran Divya, Vallikannan Baskaran
Topics & Concepts
AngiogenesisRetinal pigment epitheliumEndocrinologyOxidative stressInternal medicineReactive oxygen speciesHypoxia (environmental)Diabetic retinopathyVascular endothelial growth factorBiologyUnfolded protein responseRetinalDiabetes mellitusEndoplasmic reticulumChemistryCell biologyMedicineBiochemistryOxygenVEGF receptorsOrganic chemistryRetinal Diseases and TreatmentsGlaucoma and retinal disordersRetinal Imaging and Analysis