Enhanced delivery of CRISPR/Cas9 system based on biomimetic nanoparticles for hepatitis B virus therapy
Kexin Wu, Miao He, Binli Mao, Yangchen Xing, Shiqi Wei, Dongjun Jiang, Shunyao Wang, Asma A. Alkuhali, Jinjun Guo, Zongjie Gan, Man Li, Xiaosong Li, Huali Chen
Topics & Concepts
cccDNACas9EndocytosisHepatitis B virusChemistryCRISPRGenetic enhancementTransfectionIn vitroGene deliveryMolecular biologyGenome editingIn vivoCell biologyVirologyVirusBiologyCellBiochemistryHBsAgGeneBiotechnologyRNA Interference and Gene DeliveryCRISPR and Genetic EngineeringVirus-based gene therapy research