Design of nanoconstructs that exhibit enhanced hemostatic efficiency and bioabsorbability
Rana A. Eissa, Hesham A. Saafan, Aliaa E. Ali, Kamilia M. Ibrahim, Noura G. Eissa, Mostafa A. Hamad, Ching Pang, Hongming Guo, Hui Gao, Mahmoud Elsabahy, Karen L. Wooley
Abstract
, degradable) hemostatic supramolecular structures and nanoconstructs have afforded the development of smart devices and scaffolds capable of efficiently controlling bleeding while degrading over time, thereby reducing surgical operation times and hospitalization duration. The nanoconstructs that are highlighted have demonstrated hemostatic efficiency pre-clinically in animal models, while also sharing characteristics of degradability, bioabsorbability and presence of nano-assemblies within their compositions.
Topics & Concepts
NanotechnologyMaterials scienceHemostasis and retained surgical itemsElectrospun Nanofibers in Biomedical ApplicationsPolymer Surface Interaction Studies