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Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

Evgenii N. Tcyganov, Emilio Sanseviero, Douglas Marvel, Thomas Beer, Hsin‐Yao Tang, Peter Hembach, David W. Speicher, Qianfei Zhang, Laxminarasimha Donthireddy, Mostafa Ali, Sabina Tsyganova, В. М. Писарев, Terri M. Laufer, Dmitriy Ignatov, Soldano Ferrone, Christiane Meyer, Hélène Maby–El Hajjami, Daniel E. Speiser, Sooner Altiok, Scott Antonia, Xiaowei Xu, Wei Xu, Cathy Zheng, Lynn M. Schuchter, Ravi K. Amaravadi, Tara C. Mitchell, Giorgos C. Karakousis, Zhe Yuan, Luis J. Montaner, Esteban Celis, Dmitry I. Gabrilovich

2022Cancer Cell50 citationsDOIOpen Access PDF

Topics & Concepts

ImmunotherapyTumor microenvironmentCytotoxic T cellCancer immunotherapyCancer researchPeroxynitriteMelanomaAntigenEpitopeImmunologyCancerMHC class IImmune systemMajor histocompatibility complexBiologyMedicineIn vitroInternal medicineBiochemistryEnzymeSuperoxideImmune cells in cancerCancer Immunotherapy and BiomarkersChemokine receptors and signaling
Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy | Litcius