Stimuli-responsive ferroptosis for cancer therapy
Nayeon Kang, Subin Son, Sunhong Min, Hyunsik Hong, Chowon Kim, Jusung An, Jong Seung Kim, Heemin Kang
Abstract
) as exogenous stimuli that can provide on-demand remote controllability for customized deep tumor therapy with a low inter-patient variation. Strikingly, the utilization of dual endogenous and/or exogenous stimuli provides a new direction for efficient cancer therapy. This review highlights recent advances in the utilization of various endogenous and exogenous stimuli to activate the reactions of nanocarriers for ferroptosis-based cancer therapy that can inspire the field of cancer therapy, particularly for the treatment of intractable tumors.
Topics & Concepts
NanocarriersCancer therapyCancerCancer drugsEndogenyDrugCancer treatmentCancer researchMedicineComputational biologyPharmacologyBiologyInternal medicineFerroptosis and cancer prognosisNanoplatforms for cancer theranosticsRNA modifications and cancer