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Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation

Elisa Giacomelli, Björn F. Vahsen, Elizabeth L. Calder, Yinyan Xu, Jakub Scaber, Elizabeth Gray, Ruxandra Dafinca, Kevin Talbot, Lorenz Studer

2022Cell stem cell102 citationsDOIOpen Access PDF

Topics & Concepts

Amyotrophic lateral sclerosisNeuroscienceTranslation (biology)BiologyBasic scienceBasic researchMultiple sclerosisFunction (biology)DiseaseCentral nervous systemCell survivalStem cellCellNervous systemDegenerative diseaseInduced pluripotent stem cellNeurodegenerationDegenerative DisorderLoss functionAnimal modelSOD1NeuroprotectionCell functionBioinformaticsMedicineAmyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation | Litcius