The copper-catalyzed oxidative radical process of site selective C–N bond cleavage in twisted amides: batch and continuous-flow chemistry
Karthick Govindan, Nian‐Qi Chen, Hsing‐Yin Chen, Sodio C. N. Hsu, Wei‐Yu Lin
Abstract
Copper-superoxo radical activation in twisted amides which mediates the aerobic oxidative process to produce primary amides by selective C–N bond cleavage in batch and continuous-flow method.
Topics & Concepts
ChemistryCatalysisCopperBond cleavageOxidative phosphorylationCleavage (geology)Continuous flowMedicinal chemistryCombinatorial chemistryPhotochemistryOrganic chemistryMaterials scienceBiochemistryComposite materialPhysicsMechanicsFracture (geology)Chemical Synthesis and AnalysisRadical Photochemical ReactionsCatalytic Cross-Coupling Reactions