Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes
Sierra N. Cullati, A. Chaikuad, Jun‐Song Chen, Jakob Gebel, Laura Tesmer, Rezart Zhubi, José Navarrete-Perea, Rodrigo X. Guillen, Steven P. Gygi, Gerhard Hummer, Volker Dötsch, Stefan Knapp, Kathleen L. Gould
Topics & Concepts
AutophosphorylationBiologyPhosphorylationPhosphoproteomicsKinaseCell biologySchizosaccharomyces pombeBiochemistryThreonineSerineSubstrate-level phosphorylationProtein-Serine-Threonine KinasesProtein kinase AProtein phosphorylationSaccharomyces cerevisiaeYeastProtein Kinase Regulation and GTPase SignalingMetabolism, Diabetes, and CancerEnzyme Structure and Function