Vitamin C enhances the <i>ex vivo</i> proliferation of porcine muscle stem cells for cultured meat production
Jiahua Fang, Mei Li, Guoqiang Zhang, Guocheng Du, Jingwen Zhou, Xin Guan, Jian Chen
Abstract
VC stimulated porcine muscle stem cell proliferation by activating the PI3K/AKT/mTOR pathway through IGF-1 signaling.
Topics & Concepts
Ex vivoMyoDStem cellCell growthCell biologyMyostatinPI3K/AKT/mTOR pathwayMyocyteIn vivoC2C12BiologyProtein kinase BCell cycleChemistryMolecular biologyCellAndrologyMyogenesisSignal transductionSkeletal muscleEndocrinologyBiochemistryBiotechnologyMedicineVitamin C and Antioxidants ResearchMuscle Physiology and DisordersViral Infectious Diseases and Gene Expression in Insects