Litcius/Paper detail

Cobalt Catalyst Determines Regioselectivity in Ring Opening of Epoxides with Aryl Halides

Aleksandra Potrząsaj, Mateusz Musiejuk, Wojciech Chaładaj, Maciej Giedyk, Dorota Gryko

2021Journal of the American Chemical Society89 citationsDOIOpen Access PDF

Abstract

/Ni dual-catalytic system allows for the selective synthesis of linear products under blue-light irradiation, thus complementing methodologies that give access to branched alcohols. Experimental and theoretical studies corroborate the proposed mechanism involving alkylcobalamin as an intermediate in this reaction.

Topics & Concepts

RegioselectivityChemistryArylElectrophileCatalysisRing (chemistry)HalideCobaltCombinatorial chemistryOrganic chemistryAlkylPorphyrin Metabolism and DisordersCO2 Reduction Techniques and CatalystsPorphyrin and Phthalocyanine Chemistry