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Design, synthesis, docking study and urease inhibitory activity evaluation of novel 2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-N-arylacetamide derivatives

Mohammad Nazari Montazer, Mehdi Asadi, Saeed Bahadorikhalili, Faezeh Sadat Hosseini, Arash Amanlou, Mahmood Biglar, Massoud Amanlou

2021Medicinal Chemistry Research18 citationsDOI

Topics & Concepts

UreaseChemistryThioureaThio-Docking (animal)IC50Active siteEnzymeChloroacetyl chlorideStereochemistryHydrazideCombinatorial chemistryIn vitroChlorideBiochemistryOrganic chemistryMedicineNursingMicrobial Applications in Construction MaterialsEnzyme function and inhibitionSynthesis and biological activity
Design, synthesis, docking study and urease inhibitory activity evaluation of novel 2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-N-arylacetamide derivatives | Litcius