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Krüppel-like factor 5 regulates wound repair and the innate immune response in human airway epithelial cells

Alekh Paranjapye, Monali NandyMazumdar, James A. Browne, Shih‐Hsing Leir, Ann Harris

2021Journal of Biological Chemistry16 citationsDOIOpen Access PDF

Abstract

cells also showed enhanced wound closure. These data reveal a pivotal role for KLF5 in coordinating epithelial functions relevant to human lung disease.

Topics & Concepts

BiologyProinflammatory cytokineCell biologyTranscription factorChemokineInnate immune systemEnhancerMolecular biologyImmune systemImmunologyInflammationGeneGeneticsKruppel-like factors researchCancer-related gene regulationGenetic Syndromes and Imprinting
Krüppel-like factor 5 regulates wound repair and the innate immune response in human airway epithelial cells | Litcius