Ligand-based G Protein Coupled Receptor pharmacophore modeling: Assessing the role of ligand function in model development
Paige N. Castleman, Gregory L. Szwabowski, Dale Bowman, Jon C. Cole, Abby L. Parrill, Daniel L. Baker
Topics & Concepts
PharmacophoreComputational biologyIn silicoLigand (biochemistry)G protein-coupled receptorDrug discoveryFunction (biology)Drug developmentVirtual screeningChemistryComputer scienceStereochemistryReceptorPharmacologyBiologyDrugBiochemistryGeneticsGeneReceptor Mechanisms and SignalingComputational Drug Discovery MethodsNeuropeptides and Animal Physiology