Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells
Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kai‐Feng Xu, Guang‐Biao Zhou
Topics & Concepts
Ubiquitin ligaseDownregulation and upregulationUbiquitinCarcinogenTobacco smokeAryl hydrocarbon receptorCancer researchReceptorLungProtein degradationVirologyMedicineBiologyChemistryCell biologyInternal medicineBiochemistryGeneEnvironmental healthTranscription factorCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchPARP inhibition in cancer therapy