First Fluconazole-resistant Candida auris isolated from fungal otitis in Iran
Mojtaba Taghizadeh Armaki, Saeid Mahdavi Omran, Keyvan Kiakojuri, Shaghayegh Khojasteh, Jalal Jafarzadeh, Mahin Tavakoli, Hamid Badali, Iman Haghani, Tahereh Shokohi, Mohammad Taghi Hedayati, Mahdi Abastabar
Abstract
BACKGROUND AND PURPOSE: , as a new characterized pathogenic yeast, has attracted remarkable attention in the recent decade due to its rapid global emergence and multidrug resistance traits. This unique species is able to cause nosocomial outbreaks and tolerate adverse conditions; however, it has been mostly misidentified by conventional methods. CASE REPORT: otitis in an immunocompetent patient in Iran. The isolate showed minimum inhibitory concentration of ≥ 32 μg/ml for fluconazole; however, the patient was treated with topical clotrimazole and miconazole with no recurrence. CONCLUSION: isolated from otitis in Iran which was fluconazole-resistant, unlike the first Iranian isolate.