Inhibitors of Antibiotic Resistance Mechanisms: Clinical Applications and Future Perspectives
Barbara Parrino, Daniela Carbone, Girolamo Cirrincione, Patrizia Diana, Stella Cascioferro
Abstract
Bacterial strains responsible for antibiotic resistant infections are increasing in an alarming way and the evolution of resistance mechanisms seems to be unstoppable. In the past decade, many efforts have been made in order to counteract this phenomenon but very few compounds have reached clinical trials. The development of new classes of antibiotics able to overcome the main bacterial drug resistance mechanisms is urgently required to counter the imminent danger of a postantibiotic era.
Topics & Concepts
AntimicrobialHumanitiesAntibioticsLibrary scienceBiologyArtMicrobiologyComputer scienceAntibiotic Resistance in BacteriaBacterial biofilms and quorum sensingAntimicrobial Peptides and Activities