Improving the thermostability of trehalose synthase from Thermomonospora curvata by covalent cyclization using peptide tags and investigation of the underlying molecular mechanism
Yao Chen, Yang Zhao, Xue Zhou, Nian Liu, Dengming Ming, Liying Zhu, Ling Jiang
Topics & Concepts
ThermostabilityChemistryTrehaloseBiocatalysisMutagenesisEnzymeProtein engineeringPeptideMolecular dynamicsMutantATP synthaseSolventBiochemistryStereochemistryCombinatorial chemistryReaction mechanismComputational chemistryCatalysisGeneEnzyme Production and CharacterizationBiochemical and Structural CharacterizationTransgenic Plants and Applications