Female Genital Schistosomiasis Lesion Resolution Post-Treatment with Praziquantel in Zambian Adults
Chishiba Kabengele, Sepo Mwangelwa, William Kilembe, Bellington Vwalika, Mubiana Inambao, Vernon Moonga, Constance Himukumbwa, W. Evan Secor, Rachel Parker, Amanda Tichacek, Amaya L. Bustinduy, Susan Allen, Kristin M. Wall
Abstract
We evaluated changes in female genital schistosomiasis (FGS) 6 to 12 months after praziquantel treatment among 43 adult Zambian women. Most women (60%) experienced decreased FGS severity and 23% experienced complete lesion resolution. This is the first study to demonstrate a meaningful effect of praziquantel treatment of FGS in adult women.
Topics & Concepts
PraziquantelSchistosomiasisSex organMedicineLesionHelminthiasisSurgeryImmunologyBiologyHelminthsGeneticsParasites and Host InteractionsGlobal Maternal and Child HealthResearch on Leishmaniasis Studies