Flavone-1,2,3-triazole derivatives as potential α-glucosidase inhibitors: Synthesis, enzyme inhibition, kinetic analysis and molecular docking study
Manoj Dhameja, Hariom Kumar, Sirisha Kurella, Uma Adepally, Preeti Gupta
Topics & Concepts
ChemistryActive siteDocking (animal)StereochemistryUncompetitive inhibitorAcarboseEnzymeIC501,2,3-TriazoleSubstituentCombinatorial chemistry1,2,4-TriazoleNon-competitive inhibitionBiochemistryOrganic chemistryIn vitroMedicineNursingNatural Antidiabetic Agents StudiesSynthesis and biological activityClick Chemistry and Applications