Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
Kousuke Mouri, Michael H. Guo, Carl G. de Boer, Michelle M. Lissner, Ingrid A. Harten, Gregory A. Newby, Hannah A. DeBerg, Winona F. Platt, Matteo Gentili, David R. Liu, Daniel Campbell, Nir Hacohen, Ryan Tewhey, John Ray
Topics & Concepts
BiologyAlleleChromatinGeneticsLocus (genetics)Computational biologyGeneEffectorAutoimmune diseaseTranscriptomeGenome-wide association studyGene expressionImmunologyGenotypeSingle-nucleotide polymorphismAntibodyT-cell and B-cell ImmunologyImmune Cell Function and Interactioninterferon and immune responses