Efficacy of Linezolid-Based Hydrogel as Local Drug in Stage II Grade A Periodontitis-A Clinical Study

Abstract

To prepare and characterize linezolid-based hydrogel and evaluate its efficacy as local drug delivery in stage II grade A periodontitis. Linezolid-based hydrogel was prepared. Hemolysis assay was done at various concentrations (2%, 4%, 6%, 8%, 10%) and a biocompatibility test was performed by MTT Assay. Forty patients with stage II grade A periodontitis were involved in this clinical trial. Participants were split into two groups. Group A (control) received only scaling and root planing (SRP) an

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