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Crocin extends lifespan by mitigating oxidative stress and regulating lipid metabolism through the DAF-16/FOXO pathway

A Li, Dan Li, Xin Tan, Rui‐Hua Xu, Linxi Mao, Ji Hye Kang, Sheng‐Hong Li, Yan Liu

2025Food & Function12 citationsDOI

Abstract

by mitigating oxidative stress and modulating lipid metabolism through the DAF-16/FOXO pathway. These results highlight the potential of crocin as a promising strategy for treating aging and age-related diseases.

Topics & Concepts

CrocinOxidative stressCrocus sativusLipid metabolismChemistryOxidative metabolismCrocusMetabolismOxidative phosphorylationBiochemistryCell biologyBiologyBotanyMedicinal Plants and Bioactive CompoundsFOXO transcription factor regulationApelin-related biomedical research
Crocin extends lifespan by mitigating oxidative stress and regulating lipid metabolism through the DAF-16/FOXO pathway | Litcius