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A Case of Spontaneous Renal Haemorrhage (Wunderlich Syndrome) in an Anticoagulated Patient

Manuela Giovini, Erika Poggiali, Piervito Zocchi, Esterina Bianchi, Elio Antonucci, Mario Barbera

2022European Journal of Case Reports in Internal Medicine18 citationsDOIOpen Access PDF

Abstract

Spontaneous renal haemorrhage is a rare but severe condition known as Wunderlich syndrome (WS). The classic presentation includes sudden-onset flank pain, a palpable flank mass and hypovolaemic shock (Lenk's triad). WS can be due to neoplasms, vascular diseases, cystic rupture, coagulopathies and infections. A contrast-enhanced CT scan of the abdomen is mandatory for diagnosis. Surgery is reserved for haemodynamically unstable patients and those with neoplastic disease. We describe a case of WS in an anticoagulated patient with chronic atrial fibrillation, diabetes mellitus type 2 and hypertension, who developed acute renal failure and severe anaemia, that completely resolved with conservative treatment and discontinuation of anticoagulation therapy. LEARNING POINTS: Wunderlich syndrome refers to spontaneous renal or perinephric haemorrhage.Contrast-enhanced CT of the abdomen is the gold standard for diagnosis.Surgery should be reserved for haemodynamically unstable patients or those with neoplastic disease.

Topics & Concepts

MedicineDiscontinuationSurgeryShock (circulatory)AbdomenFlank painAbdominal painPresentation (obstetrics)RadiologyTuberous Sclerosis Complex ResearchRenal cell carcinoma treatmentAmyloidosis: Diagnosis, Treatment, Outcomes