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Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore

Juan M. Saavedra

2021Physiology31 citationsDOI

Abstract

Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and cognition, properties useful to treat inflammatory, age-related, neurodegenerative, and metabolic disorders of many organs including brain and lung.

Topics & Concepts

InflammationCoagulation cascadeMedicineAngiotensin IIInsulin resistanceReceptorBlood pressureAngiotensin II receptor type 1Immune systemCoagulationInternal medicinePharmacologyInsulinImmunologyThrombinPlateletRenin-Angiotensin System StudiesApelin-related biomedical researchBlood Pressure and Hypertension Studies
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