ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update
Robin Lovell‐Badge, Eric Anthony, Roger A. Barker, Tania Bubela, Ali H. Brivanlou, Melissa Carpenter, R. Alta Charo, Amander T. Clark, Ellen Wright Clayton, Yali Cong, George Q. Daley, Jianping Fu, Misao Fujita, Andy Greenfield, Steve A. Goldman, Lori R. Hill, Insoo Hyun, Rosario Isasi, Jeffrey Kahn, Kazuto Kato, Jin‐Soo Kim, Jonathan Kimmelman, Juergen A. Knoblich, Debra Mathews, Núria Montserrat, Jack T. Mosher, Megan Munsie, Hiromitsu Nakauchi, Luigi Naldini, Gail K. Naughton, Kathy K. Niakan, Ubaka Ogbogu, Roger Pedersen, Nicolas Rivron, Heather M. Rooke, Janet Rossant, Jeff Round, Mitinori Saitou, Douglas Sipp, Julie Steffann, Jeremy Sugarman, M. Azim Surani, Jun Takahashi, Fuchou Tang, Leigh Turner, Patricia J. Zettler, Xiaomei Zhai
Abstract
The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy issues that have arisen since the last update in 2016. While growing to encompass the evolving science, clinical applications of stem cells, and the increasingly complex implications of stem cell research for society, the basic principles underlying the Guidelines remain unchanged, and they will continue to serve as the standard for the field and as a resource for scientists, regulators, funders, physicians, and members of the public, including patients. A summary of the key updates and issues is presented here.