Facile and stereospecific synthesis of diverse β-<i>N</i>-glycosyl sulfonamide scaffolds <i>via</i> palladium catalysis
Lei Zhong, Qunliang Wang, Yujuan Wang, Yiyang Cheng, Yimeng Xiong, Haibo Peng, Zhen Zhou, Yun He, Yuanwei Dai
Abstract
a late-stage diversification strategy and various facile synthetic transformations of the products. Collectively, the established protocol provides a valuable tool for efficiently preparing glycosyl sulfonamides to facilitate drug discovery.
Topics & Concepts
StereospecificityPalladiumSulfonamideGlycosylChemistryCatalysisCombinatorial chemistryStereochemistryOrganic chemistryCarbohydrate Chemistry and SynthesisSulfur-Based Synthesis TechniquesPneumocystis jirovecii pneumonia detection and treatment