Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand
Yuxin Duan, Fania Szlam, Yuesong Hu, Wenchun Chen, Renhao Li, Yonggang Ke, Roman M. Sniecinski, Khalid Salaita
Topics & Concepts
ChemistryBiophysicsPlateletCell biologyCleavage (geology)CellDuplex (building)Reporter geneReceptorMolecular biologyDNABiochemistryGeneBiologyGene expressionImmunologyFracture (geology)PaleontologyCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchRNA Interference and Gene Delivery