Pathogenesis of rheumatoid arthritis: one year in review 2023
Francesco Mariani, Irene Martelli, Francesca Pistone, Erica Chericoni, Ilaria Puxeddu, Alessia Alunno
Abstract
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by local and systemic inflammation. The complex interplay between immune cells and soluble mediators leads to the induction and perpetuation of aberrant inflammatory and autoimmune responses. The research carried out in the last year in the field of RA enabled the identification of new mechanisms involved in the pathogenesis of the disease and therefore unmasked new potential therapeutic targets. In this review article we summarised the new insights into RA pathogenesis from original research articles published in the last year.
Topics & Concepts
MedicinePathogenesisRheumatoid arthritisImmunologyAutoimmune diseaseInflammationDiseaseArthritisImmune systemBioinformaticsPathologyAntibodyBiologyRheumatoid Arthritis Research and TherapiesSystemic Lupus Erythematosus ResearchMonoclonal and Polyclonal Antibodies Research