Aerobic Oxidative Functionalization of Indoles
Saiwen Liu, Feng Zhao, Xing Chen, Guo‐Jun Deng, Huawen Huang
Abstract
Abstract The synthetic methodology for direct indole functionalizations is of great significance in indole chemistry and has been intensively investigated in the last few decades. From the perspective of green chemistry, oxygen is the best choice as the terminal oxidant in molecular synthesis. Hence, aerobic oxidative functionalization of indoles became a hot research topic in the last decade. Numerous efficient protocols in this field have been discovered that enable facile and efficient transformations of indoles to related valuable compounds, which are summarized and discussed in detail in this review. magnified image
Topics & Concepts
ChemistrySurface modificationIndole testOxidative phosphorylationCombinatorial chemistryMolecular oxygenOrganic chemistryNanotechnologyOxygenBiochemistryPhysical chemistryMaterials scienceCatalytic C–H Functionalization MethodsOxidative Organic Chemistry ReactionsSynthesis and Catalytic Reactions