A Comprehensive Review on Anxiolytic Effect of <scp> <i>Lavandula Angustifolia</i> </scp> Mill. in Clinical Studies
Sana Manzoor, Allah Rakha, Hina Rasheed, Zuhaib F. Bhat, Md. Akhtaruzzaman Khan, Gholamreza Abdi, Rana Muhammad Aadil
Abstract
, a fragrant but bitter flower generally termed lavender, has been exploited for years as a therapy for distinct ailments. It can act as an antispasmodic, analgesic, hypotensive, antiseptic, antimicrobial, and tonic effects that promoting overall health and vitality. This review critically appraises the major bioactive components of lavender and their anxiolytic effects. These key elements interact with the nervous and endocrine systems to modulate the pathophysiology and improve mood and behavior. They modulate the GABA receptors to relax the neurons, spare more serotonin in synapses, and channelize neurotransmitters through distinct signaling cascades. Several clinical trials have demonstrated the anxiolytic potential of oral lavender, with minimal side effects, in human subjects. Therefore, exploiting the herbs for therapeutic purposes, that is, lavender for anxiety, is a safer approach to managing anxiety and preserving mental health and well-being.