Differences in local anaesthetic and antiepileptic binding in the inactivated state of human sodium channel Nav1.4
Amanda Buyan, Aidan A. Whitfield, Ben Corry
Topics & Concepts
ChemistrySodium channelLamotrigineLidocaineSodium channel blockerBiophysicsBinding siteMoietyLocal anestheticStereochemistrySodiumPharmacologyBiochemistryAnesthesiaNeuroscienceEpilepsyMedicineOrganic chemistryBiologyNeuroscience and Neuropharmacology ResearchIon channel regulation and functionEpilepsy research and treatment