Astrocytes regulate ultra-slow arteriole oscillations via stretch-mediated TRPV4-COX-1 feedback
Jordan N. Haidey, Govind Peringod, Ádám Institóris, Kelsea A. Gorzo, Wilten Nicola, Milène Vandal, Ken‐ichi Ito, Shiying Liu, Cameron Fielding, Frank Visser, Minh Dang Nguyen, Grant R. Gordon
Abstract
in vivo reduces the power of vasomotion. These data demonstrate bidirectional communication between arterioles and astrocyte endfeet to regulate oscillatory microvasculature activity.
Topics & Concepts
TRPV4ArterioleCell biologyChemistryNeuroscienceAstrocyteBiophysicsIon channelBiologyInternal medicineMedicineReceptorCentral nervous systemMicrocirculationBiochemistryNitric Oxide and Endothelin EffectsSodium Intake and HealthCardiovascular Health and Disease Prevention