Phenolic Profiling and Therapeutic Potential of Certain Isolated Compounds from <i>Parkia roxburghii</i> against AChE Activity as well as GABA<sub>A</sub> α5, GSK-3β, and p38α MAP-Kinase Genes
Heba A. El Gizawy, Heba M. Abo‐Salem, Ali Ali, Mohammed A. Hussein
Abstract
α5), glycogen synthase kinase-3 (GSK-3), p38 mitogen-activated protein kinase (p38MAP-kinase), signal-regulated kinase (ERK), and protein-serine/threonine kinase (Akt) were then determined using molecular docking.
Topics & Concepts
KinaseGSK-3CatechinPharmacologyp38 mitogen-activated protein kinasesChemistryBiochemistryProtein kinase AProtein kinase BAcetylcholinesteraseBiologyAntioxidantSignal transductionEnzymePolyphenolMedicinal Plants and NeuroprotectionNatural Antidiabetic Agents StudiesPhytochemicals and Antioxidant Activities