Mining of linear B cell epitopes of SARS-CoV-2 ORF8 protein from COVID-19 patients
Xiaohui Wang, Joy-Yan Lam, Lin‐Lei Chen, Shannon Wing‐Ngor Au, Kelvin Kai‐Wang To, Kwok‐Yung Yuen, Kin‐Hang Kok
Abstract
, demonstrating a potential application of the linear peptide-based immunization strategy. Taken together, identification and validation of these B-cell linear epitopes will provide insights into the design of serological diagnostics and peptide-based vaccination approach against this pandemic virus of high priority.
Topics & Concepts
EpitopeVirologySerologyVaccinationBiologyPandemicAntibodyVirusMedicineCoronavirus disease 2019 (COVID-19)Computational biologyImmunologyDiseaseInfectious disease (medical specialty)PathologySARS-CoV-2 and COVID-19 ResearchRespiratory viral infections researchSARS-CoV-2 detection and testing