Mitochondria specific highly cytoselective iridium(<scp>iii</scp>)–Cp* dipyridophenazine (dppz) complexes as cancer cell imaging agents
Nilmadhab Roy, Utsav Sen, Shreya Ray Chaudhuri, Venkatesan Muthukumar, Prithvi Moharana, Priyankar Paira, Bipasha Bose, Ashna Gauthaman, Anbalagan Moorthy
Abstract
-Cp*)IrCl(11-(trifluoromethyl)dipyrido[3,2-a:2',3'-c]phenazine (IrL5) came into the limelight as the best theranostic agent as it showed remarkable cytoselectivity as well as significant cellular imaging properties, endowing it with the highest quantum yield value among all the complexes.
Topics & Concepts
IridiumMitochondrionChemistryStereochemistryBiochemistryCatalysisLanthanide and Transition Metal ComplexesMetal complexes synthesis and propertiesNanoplatforms for cancer theranostics