Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells
Liraz Shmuel-Galia, Fiachra Humphries, Xuqiu Lei, Simona Ceglia, Ruth Wilson, Zhaozhao Jiang, Natália Ketelut-Carneiro, Sage E. Foley, Susanne Pechhold, JeanMarie Houghton, Khaja Muneeruddin, Scott A. Shaffer, Beth A. McCormick, Andrea Reboldi, Doyle V. Ward, Ann Marshak‐Rothstein, Katherine A. Fitzgerald
Topics & Concepts
Innate immune systemBiologyStingSignal transducing adaptor proteinUbiquitinImmunologyMyeloid cellsMyeloidDysbiosisImmune systemCancer researchCell biologySignal transductionGut floraGeneticsEngineeringAerospace engineeringGeneinterferon and immune responsesInflammasome and immune disordersImmune Cell Function and Interaction