Engineered mesenchymal stem cell exosomes loaded with miR-34c-5p selectively promote eradication of acute myeloid leukemia stem cells
Jin Wen, Ying Chen, Chenxi Liao, Xiao Ma, Mengyuan Wang, Qian Li, Di Wang, Yingnan Li, Xiaolan Zhang, Lei Li, Hao Zhou, Jing Zou, Lingbo Liu, Danyue Peng
Topics & Concepts
Mesenchymal stem cellHoming (biology)MicrovesiclesStem cellMyeloid leukemiaHaematopoiesisCancer researchLeukemiaExosomeImmunologyBone marrowMedicineBiologyCell biologymicroRNAEcologyBiochemistryGeneExtracellular vesicles in diseaseMicroRNA in disease regulationRNA Interference and Gene Delivery