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Iron overload induces apoptosis of osteoblast cells via eliciting ER stress-mediated mitochondrial dysfunction and p-eIF2α/ATF4/CHOP pathway in vitro

Jingmin Che, Huanhuan Lv, Jiancheng Yang, Bin Zhao, Si-Bo Zhou, Tongyao Yu, Peng Shang

2021Cellular Signalling57 citationsDOI

Topics & Concepts

ApoptosisUnfolded protein responseCell biologyMitochondrionEndoplasmic reticulumBiologyCHOPReactive oxygen speciesChemistryEndocrinologyInternal medicineBiochemistryMedicineTrace Elements in HealthEndoplasmic Reticulum Stress and DiseaseRNA regulation and disease
Iron overload induces apoptosis of osteoblast cells via eliciting ER stress-mediated mitochondrial dysfunction and p-eIF2α/ATF4/CHOP pathway in vitro | Litcius