Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening
Zhongyuan Luo, Daohai Du, Y. Liu, Tian Lu, Liping Liu, Hualiang Jiang, Kaixian Chen, Changliang Shan, Cheng Luo
Topics & Concepts
ChemistryHigh-throughput screeningNicotinamide adenine dinucleotide phosphateDehydrogenaseGlucose-6-phosphate dehydrogenaseBiochemistryEnzymeIC50Drug discoverySurface plasmon resonanceChemical libraryIn vitroSmall moleculeOxidase testNanotechnologyNanoparticleMaterials sciencebioluminescence and chemiluminescence research3D Printing in Biomedical ResearchNanoplatforms for cancer theranostics