Litcius/Paper detail

Non-enzymatic electrochemical detection of creatinine based on a glassy carbon electrode modified with a Pd/Cu<sub>2</sub>O decorated polypyrrole (PPy) nanocomposite: an analytical approach

A. Nagarajan, V. Sethuraman, R. Sasikumar

2023Analytical Methods30 citationsDOI

Abstract

O/PPy nanocomposite, which was characterized by different analytical methods. The present electrochemical sensor provides a wide detection range (0.1 to 150 μM), low detection limit (0.05 μM) and high sensitivity (0.207 μA), and is capable of detecting the creatinine level in human urine samples, which are inexpensive. The results are reproducible, and the sensor is stable. The sensor demonstrates good electrocatalytic activity and selectivity towards the detection of creatinine in the presence of various other similar biological entities. When compared to other existing counterparts, the electrocatalytic behaviour of the present sensor is comparable, if not better. So, the present electrochemical sensor for creatinine might be employed as a long-term diagnostic alternative.

Topics & Concepts

PolypyrroleNanocompositeMaterials scienceCreatinineElectrodeElectrochemistryGlassy carbonCarbon fibersChemical engineeringInorganic chemistryNanotechnologyChemistryComposite materialCyclic voltammetryComposite numberPhysical chemistryBiochemistryEngineeringElectrochemical sensors and biosensorsConducting polymers and applicationsAnalytical Chemistry and Sensors