Failure to EGFR-TKI-based therapy and tumoural progression are promoted by MEOX2/GLI1-mediated epigenetic regulation of EGFR in the human lung cancer
Irlanda Peralta‐Arrieta, Octavio A. Trejo-Villegas, Leonel Armas‐López, Hugo A. Ceja-Rangel, María del Carmen Ordóñez-Luna, priscila pineda villegas, Marco A. González-López, Blanca Ortíz-Quintero, Criselda Mendoza-Milla, Zyanya Lucía Zatarain-Barrón, Óscar Arrieta, Joaquı́n Zúñiga, Federico Ávila‐Moreno
Topics & Concepts
BiologyCancer researchGLI1ErlotinibEpidermal growth factor receptorCancerLung cancerOncogeneInternal medicineSignal transductionHedgehogGeneticsMedicineCell cycleLung Cancer Treatments and MutationsHedgehog Signaling Pathway StudiesGlioma Diagnosis and Treatment