Zinc-Responsive Regulator Zur Regulates Zinc Homeostasis, Secondary Metabolism, and Morphological Differentiation in Streptomyces avermitilis
Mengya Lyu, Yaqing Cheng, Yujie Dai, Ying Wen, Yuan Song, Jilun Li, Zhi Chen
Abstract
Biosynthesis of secondary metabolites and morphological differentiation in bacteria are affected by environmental signals. The molecular mechanisms whereby zinc availability affects secondary metabolism and morphological differentiation remain poorly understood.
Topics & Concepts
Streptomyces avermitilisRegulatorZincBiologySecondary metabolismHomeostasisStreptomycesMicrobiologyCell biologyBiochemistryChemistryGeneticsBacteriaBiosynthesisEnzymeGeneOrganic chemistryTrace Elements in HealthMicrobial Natural Products and BiosynthesisTuberculosis Research and Epidemiology