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Intracellular calcium leak as a therapeutic target for RYR1-related myopathies

Alexander Kushnir, Joshua J. Todd, Jessica W. Witherspoon, Qi Yuan, Steven Reiken, Harvey Lin, Ross H. Munce, Benjamin Wajsberg, Zephan Melville, Oliver B. Clarke, Kaylee Wedderburn-Pugh, Anetta Wronska, Muslima S. Razaqyar, Irene C. Chrismer, Monique O. Shelton, Ami Mankodi, Christopher Grunseich, Mark A. Tarnopolsky, Kurenai Tanji, Michio Hirano, Sheila Riazi, Natalia Kraeva, Nicol C. Voermans, Angela Gruber, Carolyn Allen, Katherine G. Meilleur, Andrew R. Marks

2020Acta Neuropathologica67 citationsDOIOpen Access PDF

Topics & Concepts

RYR1Ryanodine receptorSkeletal muscleBiologyCalciumGeneticsEndoplasmic reticulumMedicineInternal medicineEndocrinologyIon channel regulation and functionCardiac electrophysiology and arrhythmiasMitochondrial Function and Pathology
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